Following
an interim analysis, Endocyte
(ECYT-$11.40) reported last Thursday that the independent Drug Safety
Monitoring Board (DSMB) advised investigators to tell non-small cell lung
cancer patients enrolled in the TARGET study that vintafolide use in
monotherapy was unlikely to prove superior to docetaxel in progression-free
survival (PFS) at the termination of the study.
However,
news that the DSMB observed the combo arm of the TARGET study (vintafolide
& taxotere) was trending toward the statistical goal of a 50% improvement
in PFS relative to the taxotere arm (and didn’t demonstrate any new safety
concerns) ultimately could prove to be good tidings for Endocyte shareholders.
Editor David J Phillips does not hold
a financial interest in any stocks mentioned in this article. The 10Q Detective
has a Full Disclosure Policy.
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